Our high-quality, Liquid Carnosine Plus © is an all-natural dietary supplement. L-Carnosine is a naturally occurring dipeptide that consists of alanine and histadine. Carnosine is most concentrated in the brain, heart, and kidneys.
have reformulated Liquid Carnosine Plus, using the same high quality
ingredients, with two changes. We now use a patented form of Zinc that
is bound (chelated) to a Carnosine molecule. Zinc-Carnosine chelate has
been cited in dozens of studies as supporting the mucosal lining of the
intestinal tract. For more information on research regarding Zinc-Carnosine please click here. We have also added Methionine which provides neurological and detoxification support.
Liquid Carnosine Plus is the highest quality, most absorbable Carnosine
supplement on the market and has the benefit of being easy to
administer in a tasty liquid form, flavored with organic lemon juice.
Carnosine recently came to national prominence due to an episode of Dr. Oz's nationally syndicated health television show that aired February 15, 2012 that highlighted Carnosine's anti-aging, anti-dementia properties.
About Liquid Carnosine Plus
Liquid Carnosine Plus is incredibly absorbable to provide great benefit. It is suitable for sensitive individuals and continues to be all-natural, it has a long shelf life and may be stored at room temperature.
1/2 teaspoon may provide a dose equivalent to a full dose of other manufacturer's comparable products, such as Carn-Aware because we use a specialized patented form of glycerine that provides a more effective delivery method for nutritional content. It is compliant with most special diets (GFCF, Low-Phenolic, Low-Oxalate) and does not contain any artificial colors, sweeteners or additives. Although you can take it straight we recommend adding it to either cool or room temperature distilled water (which helps with absorbability) or with your favorite juice. Because of vastly increased absorbability, we have reduced levels of supporting ingredients such as zinc and magnesium to avoid excessive amounts of uptake of these minerals. It is still flavored with organic lemon juice.
We were able to eliminate Vitamin C and Potassium Sorbate as preservatives because the high concentration of glycerine acts as a natural preservative.
Carnosine, Autism, and Seizure Disorders
Use of L-Carnosine in autism was pioneered by Dr. Michael Chez, a pediatric neurologist from Chicago. Dr. Chez theorized that L-Carnosine stimulates the front areas of the brain, providing increased activity, leading to overall improvements in level of functioning. More and more research shows that the frontal lobes and temporal lobes in the brain control emotion, epileptic activity, cognitive, expressive speech, and abstract thinking. It also rejuvinates old, dying cells restoring them to youthful appearance - hence it is a key anti-aging supplement as well.
In a double-blind study conducted by Dr. Chez, L-Carnosine was found to be beneficial to children with autism spectrum disorders and/or epilepsy. Participants in the clinical trial who were given L-Carnosine experienced significant improvements compared to those taking a placebo in the following areas: language, auditory processing socialization, awareness of surroundings, fine motor planning and expressive language. Improvements were observed between 1-8 weeks into treatment, with a 90 percent success rate.
Participants taking L-Carnosine showed improved behavior and communication by 16 percent and social interaction improved by 27 percent! In just four weeks, parents reported an overall improvement that more than doubled through the length of the study. To view a summary of the clinical trial, please click here.
Dr. Chez also theorized that all autistic children are dyslexic and that distortion of sensory input (touch, taste, hearing, sight) that autistic children experience are forms of dyslexia. We have anecdotal evidence from customers of all ages that their dyslexia improves or completely disappears when they supplement with Carnosine, including a young lady whose handwriting, reading skills, and grades dramatically improved in after taking Liquid Carnosine Plus over a two-month period. Dr. Chez's study also showed the reading ability took a leap when taking Carnosine.
Carnosine Research in Learning Disabilities and Dyslexia
For more information on Carnosine research related to Dyslexia and other learning disabilities, please click here.
What Makes Liquid Carnosine Plus Better?
Not all supplements are created alike, and the quality of ingredients and can make a huge difference in effectiveness. Unfortunately, the raw materials of supplements can legally contain hidden, unlabeled fillers and by-products of manufacturing that can be potentially harmful or allergenic to sensitive individuals.
Liquid Carnosine Plus provides our proprietary blend of ingredients - using only the highest quality L-Carnosine, and the highest quality magnesium-taurate and magnesium-glycinate chelates for improved absorption and utilization. Ingredients of inferior quality generally don't work as well. Many manufacturers put in less of the active ingredients than advertised on the label, as is periodically shown when consumer groups have an independent laboratory test the actual levels of ingredients in supplements purchased at chain health food stores. We do not skimp. We also enhance the effectiveness of the Carnosine including additional ingredients. Taurine and Magnesium have anti-seizure properties and appear to be most effective when taken together. Taurine has been sited as enhancing the effect of the calming neurotransmitter, GABA, as does L-Carnosine. Glycine is one of the major calming neurotransmitters in the brain, along with GABA.
It may be mixed into other drinks and smoothies if taken within 15 minutes of mixing with either cool or room temperature beverages. It is compliant with the following diets: GFCF, SCD, Low-Phenolic, Low-Oxalic diet, and Feingold.
One of the nice things about our form of Carnosine is the ease in adjusting the dosage to be that which is exactly right for you - there is no need to split open a capsule. For those who take larger amounts of Carnosine there is convenience of a quick, pleasant-tasting drink that can even be added to water, orange juice, or lemonade, instead swallowing several capsules.
Carnosine, Histamine, and Histadine
Individuals with autism tend to have elevated levels of histimines, which predisposes them to developing allergies. According to Dr. Kyriazas, a British physician and educator, Carnosine modulates the effects of histamine by binding to some of the histamine receptors, e.g. H1 and H2. When histamine is high, Carnosine will block its actions, and when histamine is low, carnosine will be used to form new histamine, maintaining a balance. The histidine molecular component of Carnosine helps to maintain the myelin sheaths, which surround and insulate nerves, and has been found beneficial for the auditory nerves. Histidine is a natural detoxifier and helps to remove heavy metals from the body and helps to protect against radiation damage.
Carnosine and Anti-Aging, Stroke, Alzheimer's, Heart Disease and Diabetes
Carnosine is a naturally occurring product in our food. But with the passing of time, levels of it decrease in the body - this is believed to be one of the primary factors leading to the aging process. Every time our cells divide, which they do throughout our lifetime, they age. Older cells are less efficient at performing the functions for which they were designed, are less efficient at creating energy and removing by products. Inefficient function of older cells leads to buildups of toxic by products and cross-linked proteins associated aging skin (wrinkles and liver spots), cataracts, and build-up of plaque in the brains of Alzheimer's patients. After about 60 divisions, cells stop reproducing and are just alive, waiting for death. However, Carnosine, when introduced into the body's cells, has been shown to rejuvenate older cells, acting an anti-aging agent from within our cell structure.
Photo A shows healthy young human cells, Photo B shows old human cells, Photo C shows old human cells supplemented with Carnosine. These cells were grown in a lab culture.
The two mice shown above are of the same age, but the Carnosine supplemented mouse had a far healthier appearance and went on to live 20% longer than its litter mate. This was not a one-time experiment, but was reproduced on many more mice.
Carnosine and High Blood Pressure, and Heart Disease
A 1992 study at Ohio University using rats found that Carnosine levels in the heart and skeletal muscles fell over 40% as they aged and were 40% lower in rats with high blood pressure. Heart muscle showed a dramatic decline. Similar correlations have been fund in humans. These authors published a second study in Biochemical Society Transactions v. 23 (1995), again showing a sharp decrease in Carnosine in the heart and skeletal muscles as they aged, especially when high blood pressure is a factor. They also found exercise was vital to keep Carnosine levels high. These means that high blood pressure may be benefit from Carnosine supplementation. I have several anecdotal reports from customers over the age of 50 that they have seen their blood pressure drop after taking Carnosine.
Carnosine and Alzheimer's
Carnosine is highly concentrated in the frontal lobes of the brain and in the olafactory bulb, which provides us with our sense of smell. This is significant in that one of the earliest symptoms of Alzheimers is losing one's sense of smell. The olfactory bulb is located in close proximity to the hippocampus, which is where short term memory is processed. There is the possibility that by protecting the region of the brain near the hippocampus, that Carnosine can help to prevent or slow down the onset of Alzheimers. Anecdotally, I have had one customer over the age of 50 tell me their sense of smell returned when they took the Carnosine for a few months and that their short-term memory also improved at the same time.
Stroke Severity Reduced Significantly with Carnosine Supplementation
In 1996, research at Michigan State Univesity conducted by Arshad Majid found that giving mice doses of Carnosine supplement before the onset of stroke consistently reduced the severity of stroke by as much as 50 percent. “That’s huge. At first I didn’t believe the results, so we repeated the test many times,” said Majid, who is also director of MSU’s Division of Cerebrovascular Disease. “These are very promising results. If you can reduce the size of the stroke by half, that means less disability for the patient.” In addition, Majid and colleagues also found that carnosine was very effective in helping to reduce the severity of stroke after the onset of symptoms. “We found that the protection was somewhat reduced, but still around 30 to 40 percent,” he said. “Again, that’s a huge number.” “The real beauty of this medication is it’s nontoxic,” Majid said. “The clot-busting medications we now give to stroke patients can be dangerous. Plus the patient needs careful neurological assessment, a CT scan and lab work before the clot-busting medication can be administered.” I spoke with Dr. Majid in January 2009 and he is continuing on with his research the use of Carnosine to treat strokes as he is seeing such promise in this area.
In the Russian Journal Byull. Eksp. Biol. Med. doctors at the Omsk Medical Institute studied rats by reviving them from induced death. They gave them injections to kill them, revived them and then injected half of them with carnosine. The ones given the carnosine not only had a higher survival rate, but less damage from being clinically dead for about five minutes. You may not like studies such as this, but much was learned from it.
Carnosine and Diabetes
In the journal Nutrition Research v. 14, (1994) researchers at the University of Quebec in Canada found that dogs given carnosine in their food regulated their insulin and glucagon secretion by affecting the pancreas. This has obvious potential for our extreme rates of diabetes and other blood sugar problems. It is believed to protect against kidney failure that can result from high levels of glucose in diabetics - by preventing scarring of the kidneys and by lowering levels of glucose in the blood as well. King’s College in London was granted a World Patent (meaning the European Community) for helping relieve diabetes with carnosine supplementation. Diabetes and blood sugar problems are now affecting our children as well as adults.
More Research on Carnosine and Age Related Conditions
For more information on research related to other conditions including Dyslexia, Alzheimer's and Parkinson's, that may benefit from L-Carnosine supplementation, please click here.
Active Ingredients per 1 Tablespoon Serving for an adult:
L-Carnosine - 250 Mg*
Zinc-Carnosine Chelate - 1.2 Mg (6.6% Daily Value)
Magnesium Taurinate - 10 Mg*
Magnesium Glycinate - 12 Mg*
Methionine - 2 mg
This product is free of ingredients derived from gluten, casein, corn, soy and other common allergens.
*Daily Value not established
Kosher Certified Vegetable Glycerin, Purified Water, Lemon Juice (organic, from concentrate)
In early release of Liquid Carnosine Plus, we are finding that a little bit of this product goes a longer way even our previously highly potent version of the product - hence we have revised the recommended dosage. We theorize that less is needed because of the higher quality ingredients plus the more absorbable liquid form. This results in a considerable cost savings - where a single dose may cost less than half of comparable encapsulated products. The recommended dosage is:
50 pounds or under - 1/8 to 1/4 teaspoon per day to start
50-100 pounds - 1/4 to1/2 teaspoon per day to start
120 pounds or up - 1/2-1 teaspoon per day to start
Because it is more concentrated, it may be perceived have a somewhat stronger taste than the previous version. We recommend adding it to 4-8 oz of cool or room temperature distilled water (distilled water promotes more effective absorption) or your favorite cool or room temperature juice, such as orange juice.
Vitamin E can be taken with Liquid Carnosine Plus to further enhance its effectiveness because most forms of vitamin E contain soy, which is an allergen for a significant number of sensitive individuals. If soy is not an allergen and you are already takes a daily multi-vitamin with Vitamin E, additional Vitamin E supplementation may not be necessary. For information on Autism Coach's Vitamin E, please click here.
This product contains no products derived from wheat, dairy, corn or soy, nor does it contain artificial colors, flavors, or sweeteners. It is compliant with the following special diets: Gluten-Free/Casein-Free, Low-Phenolic, Feingold, and Low-Oxalate.
Can store with cap closed at room temperature between 65 and 80 degrees. Farenheit, 18-26 degrees Celsius.
Important: Before using a dosage higher than those recommended above, parents should consult with the child's physician or neurologist.
Dosage is relative to age, weight, autistic or epileptic issues and is also relative to EEG activity and particular learning disabilities and or dietary issues.
Children with other disorders such as epilepsy, central processing disorder, or brain injury have received dosages that have ranged from 200 to 3000 mg per day of L-Carnosine, based upon evaluation by your child's neurologist. Many neurologists using L-Carnosine recommend higher dosages to address seizure disorders, but higher dosages are best worked up to and used under the supervision of the child's neurologist. If the child has previously used another Carnosine supplement, we recommend beginning with one quarter dosage of Carnosine per serving previously used (or 1/2 dosage if using our previous version of Carnosine), and if it is needed, gradually working up to the desired level.
Side Effects: The primary side-effects are hyperactivity and irritability, which appear to fade away for the majority of individuals, when the dosage is reduced. It is recommended that hyperactive children take methylated forms Vitamin B6, B12 and folic acid (100 - 200 mg per day) with L-Carnosine, though again this should be determined by the child's physician. Methylated forms of these B vitamins are P5P (B6), Methylcobalamin (B12), and folinic acid (folic acid). The combination of B6 and the magnesium was pioneered by Dr. Bernard Rimland in the treatment of autism and has been in use for over 25 years. We have heard from parents that methylated B vitamin supplementation frequently address issues of hyperactivity encountered when initially beginning supplementation with Carnosine. We offer the tasty, liquid Behavior Balance to provide methyl donors, our Bioactive Vitamin Mineral Powder that can be mixed into drinks or smoothies, or capsules forms of B Complex and Folinic Acid to provide this support.
Potential Drug Interactions: There have been no adverse effects reported when used with stimulants, anti-psychotic or SSRI medications, acetaminophen, ibuprofen or antibiotics. Acetyl-choline esterase inhibitors may over-stimulate in combination with L-Carnosine, but no physically adverse reactions have been noted.
Note: This product is not intended to treat, cure, or prevent any disease. Please note that supplements are non-refundable, once opened.
Liquid Carnosine Plus - Copyright © 2007-2011 Autism Coach. All Rights Reserved.