L-Carnosine is a naturally occurring
dipeptide (two molecules connected together) that consists of alanine and
histadine . L-Carnosine is most concentrated in the brain, heart, eyes and
kidneys. There is a substantial body of research, with dozens of studies (which can be found in the U.S. government’s biomedical research database, pubmed.org)
indicating L-Carnosine’s potential for neurological support.
Although we have been offering this
product for years, Carnosine came to national prominence on an episode of Dr.
Oz's nationally syndicated health television show that aired February 15, 2012
that highlighted Carnosine's anti-aging, anti-dementia properties.
About Liquid Carnosine
Our high-quality, Liquid Carnosine
Plus © is an all-natural dietary supplement.
Liquid Carnosine Plus is the highest quality, most absorbable Carnosine
supplement on the market and has the benefit of being easy to administer in a
tasty liquid form, flavored with organic lemon juice. It is suitable for
sensitive individuals and continues to be all-natural, it has a long shelf life
and may be stored at room temperature.
1/2 teaspoon may provide a dose
equivalent to a full dose of other manufacturer's comparable products, because
we use a specialized patented form of glycerine that provides a more effective
delivery method for nutritional content.
It is compliant with most special
diets (GFCF, Low-Phenolic, Low-Oxalate) and does not contain any artificial
colors, sweeteners or additives. Although you can take it straight we recommend
adding it to either cool or room temperature distilled water (which helps with
absorbability) or with your favorite juice.
Because of vastly increased
absorbability, there are smaller levels of supporting ingredients such as zinc
and magnesium than might be found in comparable products to avoid excessive
amounts of uptake of these minerals. It is flavored with organic lemon juice.
Liquid Carnosine Plus also includes a
patented form of Zinc that is bound (chelated) to a Carnosine molecule.
Zinc-Carnosine chelate has been cited in dozens of studies as supporting the
mucosal lining of the intestinal tract. For more information on research regarding
Zinc-Carnosine, please click here.
It also includes Methionine which enhances
neurological and detoxification support.
Unlike other liquid supplements it
does not contain additional preservatives (such as the neurotoxic sodium benzoate
that is frequently used) because the high concentration of glycerine acts as a
Carnosine, Autism, and Seizure Disorders
Use of L-Carnosine in autism was
pioneered by Dr. Michael Chez, a pediatric neurologist from Chicago.
Dr. Chez theorized that
L-Carnosine stimulates the front areas of the brain, providing
increased activity, leading to overall improvements in level of
and more research shows that the frontal lobes and temporal lobes in
the brain control emotion, epileptic activity, cognitive, expressive
speech, and abstract thinking.
It also rejuvinates old, dying
cells restoring them to youthful appearance - hence it is a key
anti-aging supplement as well.
In a double-blind study conducted by
Dr. Chez, L-Carnosine was found to be beneficial to children with
autism spectrum disorders and/or epilepsy.
Participants in the clinical trial who were given
L-Carnosine experienced significant improvements compared to those
taking a placebo in the following areas: language, auditory processing
awareness of surroundings, fine motor planning and expressive language.
Improvements were observed between 1-8 weeks into treatment, with a 90
percent success rate.
L-Carnosine showed improved behavior and communication by 16 percent
and social interaction improved by 27 percent! In just four weeks,
parents reported an overall improvement that more than doubled through
the length of the study. To view a summary of the clinical trial,
Dr. Chez also
theorized that all autistic children are dyslexic and that
distortion of sensory input (touch, taste, hearing, sight) that
autistic children experience are forms of dyslexia. We have
anecdotal evidence from customers of all ages that their dyslexia
improves or completely disappears when they supplement with
Carnosine, including a young lady whose handwriting, reading
skills, and grades dramatically improved in after taking Liquid
Carnosine Plus over a two-month period. Dr. Chez's study also showed the
reading ability took a leap when taking Carnosine.
Carnosine Research in
Learning Disabilities and Dyslexia
For more information on Carnosine
research related to Dyslexia and other learning disabilities, please click here.
What Makes Liquid
Carnosine Plus Better?
Not all supplements are created
alike, and the quality of ingredients and can make a huge difference in effectiveness.
Unfortunately, the raw materials of supplements can legally contain hidden,
unlabelled fillers and by-products of manufacturing that can be
potentially harmful or allergenic to sensitive individuals.
Liquid Carnosine Plus provides our
proprietary blend of ingredients - using only the highest quality L-Carnosine,
and the highest quality magnesium-taurate and magnesium-glycinate chelates for
improved absorption and utilization. Ingredients of inferior quality generally
don't work as well. Many manufacturers put in less of the active ingredients
than advertised on the label, as is periodically shown when consumer groups
have an independent laboratory test the actual levels of ingredients in
supplements purchased at chain health food stores. We do not skimp. We also
enhance the effectiveness of the Carnosine including additional ingredients.
Taurine and Magnesium have anti-seizure properties and appear to be most
effective when taken together. Taurine has been sited as enhancing the effect
of the calming neurotransmitter, GABA, as does L-Carnosine. Glycine is one of
the major calming neurotransmitters in the brain, along with GABA.
It may be mixed into other drinks and smoothies if
taken within 15 minutes of mixing with either cool or room temperature
It is compliant
with the following diets: GFCF, SCD, Low-Phenolic, Low-Oxalic diet, and
One of the nice
things about our form of Carnosine is the ease in adjusting the dosage
to be that which is exactly right for you - there is no need to split
open a capsule. For those who take larger amounts of Carnosine there is
convenience of a quick, pleasant-tasting drink that can even be added
to water, orange juice, or lemonade, instead swallowing several
Carnosine, Histamine, and Histadine
autism tend to have elevated levels of histimines, which predisposes
them to developing allergies. According to Dr. Kyriazas, a British
physician and educator, Carnosine modulates the effects of histamine by
binding to some of the histamine receptors, e.g. H1 and H2. When
histamine is high, Carnosine will block its actions, and when histamine
is low, carnosine will be used to form new histamine, maintaining a
balance. The histidine molecular component of Carnosine helps to
maintain the myelin sheaths, which surround and insulate nerves, and
has been found beneficial for the auditory nerves. Histidine is a
natural detoxifier and helps to remove heavy metals from the body and
helps to protect against radiation damage.
Carnosine and Anti-Aging, Stroke, Alzheimer's, Heart Disease and
Carnosine is a
naturally occurring product in our food. But with the passing of time,
levels of it decrease in the body - this is believed to be one of the
primary factors leading to the aging process. Every time our cells
divide, which they do throughout our lifetime, they age. Older cells
are less efficient at performing the functions for which they were
designed, are less efficient at creating energy and removing by
products. Inefficient function of older cells leads to buildups of
toxic by products and cross-linked proteins associated aging skin
(wrinkles and liver spots), cataracts, and build-up of plaque in the
brains of Alzheimer's patients. After about 60 divisions, cells stop
reproducing and are just alive, waiting for death. However, Carnosine,
when introduced into the body's cells, has been shown to rejuvenate
older cells, acting an anti-aging agent from within our cell
Photo A shows
healthy young human cells, Photo B shows old human cells, Photo C shows
old human cells supplemented with Carnosine. These cells were grown in
a lab culture.
two mice shown above are of the same age, but the Carnosine
supplemented mouse had a far healthier appearance and went on to live
20% longer than its litter mate. This was not a one-time experiment,
but was reproduced on many more mice.
Carnosine and High Blood
Pressure, and Heart Disease
A 1992 study at Ohio University using
rats found that Carnosine levels in the heart and skeletal muscles fell
over 40% as they aged and were 40% lower in rats with high blood
pressure. Heart muscle showed a dramatic decline. Similar correlations
have been fund in humans. These authors published a second study in
Biochemical Society Transactions v. 23 (1995), again showing a sharp
decrease in Carnosine in the heart and skeletal muscles as they aged,
especially when high blood pressure is a factor. They also found
exercise was vital to keep Carnosine levels high. These means that high
blood pressure may be benefit from Carnosine supplementation. I have
several anecdotal reports from customers over the age of 50 that they
have seen their blood pressure drop after taking Carnosine.
Carnosine and Alzheimer's
highly concentrated in the frontal lobes of the brain and in the
olafactory bulb, which provides us with our sense of smell. This is
significant in that one of the earliest symptoms of Alzheimers is
losing one's sense of smell. The olfactory bulb is located in close
proximity to the hippocampus, which is where short term memory is
processed. There is the possibility that by protecting the region of
the brain near the hippocampus, that Carnosine can help to prevent or
slow down the onset of Alzheimers. Anecdotally, I have had one customer
over the age of 50 tell me their sense of smell returned when they took
the Carnosine for a few months and that their short-term memory also
improved at the same time.
Stroke Severity Reduced
Significantly with Carnosine Supplementation
In 1996, research at Michigan State
Univesity conducted by Arshad Majid found that giving mice doses of
Carnosine supplement before the onset of stroke consistently reduced
the severity of stroke by as much as 50 percent. “That’s huge. At first
I didn’t believe the results, so we repeated the test many times,” said
Majid, who is also director of MSU’s Division of Cerebrovascular
Disease. “These are very promising results. If you can reduce the size
of the stroke by half, that means less disability for the patient.” In
addition, Majid and colleagues also found that carnosine was very
effective in helping to reduce the severity of stroke after the onset
of symptoms. “We found that the protection was somewhat reduced, but
still around 30 to 40 percent,” he said. “Again, that’s a huge number.”
“The real beauty of this medication is it’s nontoxic,” Majid said. “The
clot-busting medications we now give to stroke patients can be
dangerous. Plus the patient needs careful neurological assessment, a CT
scan and lab work before the clot-busting medication can be
administered.” I spoke with Dr. Majid in January 2009 and he is
continuing on with his research the use of Carnosine to treat strokes
as he is seeing such promise in this area.
the Russian Journal Byull. Eksp. Biol. Med. doctors at the Omsk Medical
Institute studied rats by reviving them from induced death. They gave
them injections to kill them, revived them and then injected half of
them with carnosine. The ones given the carnosine not only had a higher
survival rate, but less damage from being clinically dead for about
five minutes. You may not like studies such as this, but much was
learned from it.
Carnosine and Diabetes
In the journal Nutrition Research v. 14, (1994) researchers at the
University of Quebec in Canada found that dogs given carnosine in their
food regulated their insulin and glucagon secretion by affecting the
pancreas. This has obvious potential for our extreme rates of diabetes
and other blood sugar problems. It is believed to protect against
kidney failure that can result from high levels of glucose in diabetics
- by preventing scarring of the kidneys and by lowering levels of
glucose in the blood as well. King’s College in London was granted a
World Patent (meaning the European Community) for helping relieve
diabetes with carnosine supplementation. Diabetes and blood sugar
problems are now affecting our children as well as adults.
More Research on Carnosine and Age Related Conditions
For more information on
research related to other conditions including Dyslexia, Alzheimer's
and Parkinson's, that may benefit from L-Carnosine supplementation,
Single adult dosage:
L-Carnosine - 250 Mg*
Zinc-Carnosine Chelate - 1.2 Mg
(6.6% Daily Value)
Magnesium Taurinate - 10 Mg*
Magnesium Glycinate - 12 Mg*
Methionine - 2 mg
This product is free of ingredients
derived from gluten, casein, corn, soy and other common allergens.
*Daily Value not established
Kosher Certified Vegetable Glycerin,
Purified Water, Lemon Juice (organic, from concentrate)
In early release of Liquid Carnosine
Plus, we are finding that a little bit of this product goes a longer way even
our previously highly potent version of the product - hence we have revised the
recommended dosage. We theorize that less is needed because of the higher
quality ingredients plus the more absorbable liquid form. This results in a
considerable cost savings - where a single dose may cost less than half of
comparable encapsulated products. The recommended dosage is:
50 pounds or under - 1/8 to 1/4
teaspoon per day to start
50-100 pounds - 1/4 to1/2 teaspoon
per day to start
120 pounds or up - 1/2-1 teaspoon
per day to start
Because it is more concentrated, it
may be perceived have a somewhat stronger taste than the previous version. We
recommend adding it to 4-8 oz of cool or room temperature distilled water
(distilled water promotes more effective absorption) or your favorite cool or
room temperature juice, such as orange juice.
Vitamin E can be taken with Liquid
Carnosine Plus to further enhance its effectiveness because most forms of
vitamin E contain soy, which is an allergen for a significant number of
sensitive individuals. If soy is not an allergen and you are already takes a
daily multi-vitamin with Vitamin E, additional Vitamin E supplementation may
not be necessary. For information on Autism Coach's Vitamin E, please click here.
This product contains no products
derived from wheat, dairy, corn or soy, nor does it contain artificial colors,
flavors, or sweeteners. It is compliant with the following special diets:
Gluten-Free/Casein-Free, Low-Phenolic, Feingold, and Low-Oxalate.
with cap closed at room temperature between 65 and 80 degrees.
Farenheit, 18-26 degrees Celsius.
using a dosage higher than those recommended above,
parents should consult with
the child's physician or neurologist.
Dosage is relative
to age, weight, autistic or epileptic issues and is also relative to
EEG activity and particular learning disabilities and or dietary
Children with other disorders
such as epilepsy, central processing disorder, or brain injury have
received dosages that have ranged from 200 to 3000 mg per day of
L-Carnosine, based upon evaluation by your child's neurologist.
using L-Carnosine recommend higher dosages to address seizure
disorders, but higher dosages are best worked up to and used under the
supervision of the child's neurologist. If the child has previously
used another Carnosine supplement, we recommend beginning with one
quarter dosage of Carnosine per serving previously used (or 1/2 dosage
if using our previous version of Carnosine), and if it is needed,
gradually working up to the desired level.
side-effects are hyperactivity and irritability, which appear to fade
away for the majority of individuals, when the dosage is
is recommended that hyperactive children take methylated forms Vitamin
B6, B12 and folic acid (100 - 200 mg per day) with L-Carnosine, though
again this should be determined by the child's physician. Methylated
forms of these B vitamins are P5P (B6), Methylcobalamin (B12), and
folinic acid (folic acid). The combination of B6 and the magnesium was
pioneered by Dr. Bernard Rimland in the treatment of autism and has
been in use for over 25 years. We have heard from parents that
methylated B vitamin supplementation frequently address issues of
hyperactivity encountered when initially beginning supplementation with
Carnosine. We offer the tasty, liquid
to provide methyl donors, our Bioactive Vitamin Mineral
that can be mixed into drinks or smoothies, or capsules
B Complex and
Folinic Acid to
provide this support.
There have been no adverse
effects reported when used with stimulants, anti-psychotic or SSRI
medications, acetaminophen, ibuprofen or antibiotics. Acetyl-choline
esterase inhibitors may over-stimulate in combination with L-Carnosine,
but no physically adverse reactions have been noted.
Note: This product is not
intended to treat, cure, or prevent any disease. Please note that
supplements are non-refundable, once opened.
Liquid Carnosine Plus - Copyright ©
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